There were 303,504 positive test results in the week to November 25, up 9.5% from the week before.
At a regional level, Northern Ireland has the highest infection rates in the UK, with 625 cases per 100,000 people, followed by South East England, with 524 cases per 100,000.
London has the lowest rate, with 318 cases per 100,000.
Meanwhile in Bristol, according to latest weekly figures up to November 20, the infection rate fell slightly with 391 new infections per 100,000 people, compared to 389 the week before.
But some areas in the city have seen a rise in infection rates.
Here are the neighbourhoods in Bristol with the biggest rise in case rates in the past week.
1. St Anne's
St Anne's has seen rates of positive Covid cases rise by 1,162 per cent, from 81cases per 100,000 people to 1,022. Photo: Google Maps
2. Stoke Bishop
Stoke Bishop has seen rates of positive Covid cases rise by 818 per cent, from 118 cases per 100,000 people in the week ending October 8 to 1,085 in the week ending October 15. Photo: Google Maps
3. Brislington
Brislington has seen rates of positive Covid cases rise by 720 per cent, from 75 cases per 100,000 people in the week ending October 8 to 617 in the week ending October 15. Photo: Google Maps
4. Headley Park
Headley Park has seen rates of positive Covid cases rise by 700 per cent, from 64 cases per 100,000 people in the week ending October 8 to 515 in the week ending October 15. Photo: Google Maps